Gas-blasting nanocapsules to accelerate carboplatin lysosome release and nucleus delivery for prostate cancer treatment

• Main Authors: Shunli Fu (Author), Shuang Liang (Author), Dandan Jiang (Author), Rui Yang (Author), Zipeng Zhang (Author), Lili Chang (Author), Xinke Zhang (Author), Yongjun Liu (Author), Na Zhang (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To improve therapeutic effect and reduce severely side effects of carboplatin (CBP), the gas-generating nanocapsules were developed to accelerate CBP lysosome release and nucleus delivery. CBP/SB-NC was prepared by co-loading CBP and NaHCO3 (SB) in nanocapsules using w/o/w emulsification solvent eva...