Gypenoside-14 Reduces Depression via Downregulation of the Nuclear Factor Kappa B (NF-kB) Signaling Pathway on the Lipopolysaccharide (LPS)-Induced Depression Model

• Main Authors: Yaqun Jiang (Author), Xiang Cheng (Author), Ming Zhao (Author), Tong Zhao (Author), Mengya Zhang (Author), Zibi Shi (Author), Xiangpei Yue (Author), Yanan Geng (Author), Jiayue Gao (Author), Chengbo Wang (Author), Junli Yang (Author), Lingling Zhu (Author)
• Format: Book
• Published: MDPI AG, 2023-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neuroinflammation is a common pathogenetic sign of depression and is closely linked to the development of depression. Many clinical anti-inflammatory drugs act as antidepressants by reducing the neuroinflammatory response. Previous research found that gypenosides and their bioactive compound gypenos...