Flavonoid Compounds Contained in Epimedii Herba Inhibit Tumor Progression by Suppressing STAT3 Activation in the Tumor Microenvironment

• Main Authors: Cheng Pan (Author), Yukio Fujiwara (Author), Hasita Horlad (Author), Daisuke Shiraishi (Author), Toyohisa Iriki (Author), Jyunko Tsuboki (Author), Tsuyoshi Ikeda (Author), Yoshihiro Komohara (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

M2-like tumor-associated macrophages (TAMs) in the tumor tissues promote tumor progression by various mechanisms and represent possible targets of antitumor therapy. In the present study, we tested whether compounds from Epimedii Herba inhibit macrophage polarization to the M2/protumorigenic phenoty...