Antioxidant Small Molecule Compound Chrysin Promotes the Self-Renewal of Hematopoietic Stem Cells

• Main Authors: Yinghui Li (Author), Mei He (Author), Wenshan Zhang (Author), Ming Yang (Author), Yahui Ding (Author), Shiqi Xu (Author), Jiali Gu (Author), Yafang Li (Author), Jingjing Yin (Author), Yingdai Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is an increasing demand for the expansion of functional human hematopoietic stem cells (hHSCs) for various clinical applications. Based on our primary screening of antioxidant small molecule compounds library, a small molecule compound C2968 (chrysin) was identificated to expand cord blood CD3...