Pathological manifestations in lymphatic filariasis correlate with lack of inhibitory properties of IgG4 antibodies on IgE-activated granulocytes.
Helminth parasites are known to be efficient modulators of their host's immune system. To guarantee their own survival, they induce alongside the classical Th2 a strong regulatory response with high levels of anti-inflammatory cytokines and elevated plasma levels of IgG4. This particular antibo...
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| Main Authors: | , , , , , , , |
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| Format: | Book |
| Published: |
Public Library of Science (PLoS),
2017-07-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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