Delineation of DNA and mRNA COVID-19 vaccine-induced immune responses in preclinical animal models

• मुख्य लेखकों: Viviane M. Andrade (लेखक), Igor Maricic (लेखक), Richa Kalia (लेखक), Lauren Jachimowicz (लेखक), Olivia Bedoya (लेखक), Daniel W. Kulp (लेखक), Laurent Humeau (लेखक), Trevor R. F. Smith (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

ABSTRACTNucleic acid vaccines are designed based on genetic sequences (DNA or mRNA) of a target antigen to be expressed in vivo to drive a host immune response. In response to the COVID-19 pandemic, mRNA and DNA vaccines based on the SARS-CoV-2 Spike antigen were developed. Surprisingly, head-to-hea...