Rational Development of Liposomal Hydrogels: A Strategy for Topical Vaginal Antiretroviral Drug Delivery in the Context of HIV Prevention

• Main Authors: Maria J. Faria (Author), Raul Machado (Author), Artur Ribeiro (Author), Hugo Gonçalves (Author), Maria Elisabete C. D. Real Oliveira (Author), Teresa Viseu (Author), José das Neves (Author), Marlene Lúcio (Author)
• Format: Book
• Published: MDPI AG, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

HIV/AIDS stands as a global burden, and vaginal microbicides constitute a promising strategy for topical pre-exposure prophylaxis. Preceding the development of a microbicide containing tenofovir disoproxil fumarate (TDF) and emtricitabine (FTC), in silico and in vitro studies were performed to evalu...