Low mitochondrial DNA copy number in peripheral blood mononuclear cells is associated with future mortality risk: a long-term follow-up study from Japan

• मुख्य लेखकों: Genki Mizuno (लेखक), Hiroya Yamada (लेखक), Yoshiki Tsuboi (लेखक), Eiji Munetsuna (लेखक), Mirai Yamazaki (लेखक), Yoshitaka Ando (लेखक), Itsuki Kageyama (लेखक), Yuki Nouchi (लेखक), Atsushi Teshigawara (लेखक), Yuji Hattori (लेखक), Ryosuke Fujii (लेखक), Hiroaki Ishikawa (लेखक), Shuji Hashimoto (लेखक), Koji Ohashi (लेखक), Nobuyuki Hamajima (लेखक), Koji Suzuki (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2024-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objectives: The mitochondrial DNA (mtDNA) is unique and circular with multiple copies of the genome. The lower mtDNA copy number (mtDNA-CN) in leukocytes is associated with the risk of all-cause mortality. However, its long-term association is unknown. Thus, the study examined the association betwee...