Integration Analysis of Pharmacokinetics and Metabolomics to Predict Metabolic Phenotype and Drug Exposure of Remdesivir

Remdesivir has displayed pharmacological activity against SARS-CoV-2. However, no pharmacometabolomics (PM) or correlation analysis with pharmacokinetics (PK) was revealed. Rats were intravenously administered remdesivir, and a series of blood samples were collected before and after treatment. Compr...

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Main Authors: Ping Du (Author), Guoyong Wang (Author), Ting Hu (Author), Han Li (Author), Zhuoling An (Author)
Format: Book
Published: Frontiers Media S.A., 2022-01-01T00:00:00Z.
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3rd Floor Main Library

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