Is fibrodysplasia ossificans progressiva an interleukin-1 driven auto-inflammatory syndrome?

• Principais autores: Ruby Haviv (Autor), Veronica Moshe (Autor), Fabrizio De Benedetti (Autor), Giusi Prencipe (Autor), Noa Rabinowicz (Autor), Yosef Uziel (Autor)
• Formato: Livro
• Publicado em: BMC, 2019-12-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background Fibrodysplasia ossificans progressiva (FOP) is the most catastrophic form of heterotopic ossification, due to ongoing intracellular signaling through the bone morphogenic protein pathway. The paroxysmal appearance of inflammatory lumps and elevated inflammatory markers during fla...