Prenylated flavonoids from Sophora flavescens inhibit mushroom tyrosinase activity and modulate melanogenesis in murine melanoma cells and zebrafish

• Main Authors: Fenling Fan (Author), Lanqing Chen (Author), Caihong Chen (Author), Song Ang (Author), Justin Gutkowski (Author), Navindra P. Seeram (Author), Hang Ma (Author), Dongli Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background:Sophora flavescens, a traditional Chinese medicine for treating conditions associated with abnormal skin pigmentation, contains flavonoids with inhibitory effects on tyrosinase. However, their mechanisms of action and their modulatory effects on melanogenesis remain unclear.Methods: Herei...