Blockade of Wnt/β-Catenin Pathway Aggravated Silica-Induced Lung Inflammation through Tregs Regulation on Th Immune Responses

• Main Authors: Wujing Dai (Author), Fangwei Liu (Author), Chao Li (Author), Yiping Lu (Author), Xiaowei Lu (Author), Sitong Du (Author), Ying Chen (Author), Dong Weng (Author), Jie Chen (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

CD4+ T cells play an important role in regulating silica-induced inflammation and fibrosis. Recent studies showed that Wnt/β-catenin pathway could modulate the function and the differentiation of CD4+ T cells. Therefore, Wnt/β-catenin pathway may participate in the development and progress of silico...