Progress in the development of modulators targeting Frizzleds

• Main Authors: Junlan Chuan (Author), Wei Li (Author), Shengliu Pan (Author), Zhongliang Jiang (Author), Jianyou Shi (Author), Zhenglin Yang (Author)
• Format: Book
• Published: Elsevier, 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Frizzleds (FZDs) receptors on the cell surface belong to the class F of G protein-coupled receptors (GPCRs) which are the major receptors of WNT protein that mediates the classical WNT signaling pathway and other non-classical pathways. Besides, the FZDs also play a core role in tissue regenerat...