Molecular docking, synthesis and in vitro antimalarial evaluation of certain novel curcumin analogues

• Egile Nagusiak: Chandrajit Dohutia (Egilea), Dipak Chetia (Egilea), Kabita Gogoi (Egilea), Dibya Ranjan Bhattacharyya (Egilea), Kishore Sarma (Egilea)
• Formatua: Liburua
• Argitaratua: Universidade de São Paulo, 2018-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

ABSTRACT The receptor protein PfATP6 has been identified as the common target of artemisinin and curcumin. The work was initiated to assess the antimalarial activity of six curcumin derivatives based on their binding affinities and correlating the in silico docking outcome with in vitro antimalarial...