Effect of acute fentanyl treatment on synaptic plasticity in the hippocampal CA1 region in rats

• Main Authors: Hai eTian (Author), Yueming eXu (Author), Fucun eLiu (Author), Guowei eWang (Author), Sanjue eHu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2015-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Postoperative cognitive dysfunction (POCD), mainly characterized by short-term decline of learning and memory, occurs after operations under anesthesia. However, the underlying mechanisms are poorly understood. The μ-opioid receptors (MOR) are highly expressed in interneurons of hippocampus, and is...