Investigating the self-assembling of nicotinic hydrazide-based amphiphile into nano-range vesicles and its amphotericin B loading applications

• Main Authors: Kashif Hussain (Author), Abdul Jabbar (Author), Khwaja Ali Hasan (Author), Muneeb Ali (Author), Zaheer Ul-Haq (Author), Muhammad Raza Shah (Author), Saeed Ahmad Khan (Author), Md Abdur Rashid (Author), Mohsin Kazi (Author), Muhammad Naseer Abbas (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractMost of the drugs are hydrophobic and have low water solubility, therefore posing issues in their absorption and bioavailability. Nonionic surfactants improve the solubility of hydrophobic drugs by entrapping them in their lipid bilayers. Two nonionic surfactants NODNH-16 and NODNH-18 are sy...