IL-6 is associated to IGF-1Ec upregulation and Ec peptide secretion, from prostate tumors

• Main Authors: A. Armakolas (Author), A. Dimakakos (Author), C. Loukogiannaki (Author), N. Armakolas (Author), A. Antonopoulos (Author), C. Florou (Author), P. Tsioli (Author), E. Papageorgiou (Author), T. P. Alexandrou (Author), M. Stathaki (Author), D. Spinos (Author), D. Pektasides (Author), E. Patsouris (Author), M. Koutsilieris (Author)
• Format: Book
• Published: BMC, 2018-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Ec peptide (PEc), resulting from the proteolytic cleavage of the IGF-1Ec isoform, is involved in prostate cancer progression and metastasis, whereas in muscle tissue, it is associated with the mobilization of satellite cells prior to repair. Our aim is to determine the physiologi...