Inhibition of TLR4 Signalling-Induced Inflammation Attenuates Secondary Injury after Diffuse Axonal Injury in Rats

• Main Authors: Yonglin Zhao (Author), Yahui Zhao (Author), Ming Zhang (Author), Junjie Zhao (Author), Xudong Ma (Author), Tingqin Huang (Author), Honggang Pang (Author), Jiaxi Li (Author), Jinning Song (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing evidence suggests that secondary injury after diffuse axonal injury (DAI) damages more axons than the initial insult, but the underlying mechanisms of this phenomenon are not fully understood. Recent studies show that toll-like receptor 4 (TLR4) plays a critical role in promoting adaptive...