Inhibition of integrin alpha v/beta 5 mitigates the protective effect induced by irisin in hemorrhage

• Autores principales: Lijiang Wang (Autor), Supaporn Kulthinee (Autor), John Slate-Romano (Autor), Thomas Zhao (Autor), Hamsa Shanmugam (Autor), Patrycja M Dubielecka (Autor), Ling X. Zhang (Autor), Gangjian Qin (Autor), Shougang Zhuang (Autor), Y. Eugene Chin (Autor), Ting C. Zhao (Autor)
• Formato: Libro
• Publicado: Elsevier, 2023-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Introduction: Irisin plays an important role in regulating tissue stress, cardiac function, and inflammation. Integrin αvβ5 was recently identified as a receptor for irisin to elicit its physiologic function. It remains unknown whether integrin αvβ5 is required for irisin's function in modulati...