Targeting microRNA-190a halts the persistent myofibroblast activation and oxidative stress accumulation through upregulation of Krüppel-like factor 15 in oral submucous fibrosis

• Main Authors: Ming-Yung Chou (Author), Chia-Hsuan Lee (Author), Pei-Ling Hsieh (Author), Shih-Chi Chao (Author), Chuan-Hang Yu (Author), Yi-Wen Liao (Author), Shiao-Pieng Lee (Author), Cheng-Chia Yu (Author), Jun-Yang Fan (Author)
• Format: Book
• Published: Elsevier, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: Oral submucous fibrosis (OSF) is a condition characterized by inflammation and excessive collagen deposition, which has been identified as a potentially malignant disorder. Recently, several microRNAs (miRNAs) have been shown to be implicated in various disorders associated with...