Disturbances of Modulating Molecules (FOXP3, CTLA-4/CD28/B7, and CD40/CD40L) mRNA Expressions in the Orbital Tissue from Patients with Severe Graves' Ophthalmopathy

• Main Authors: Przemyslaw Pawlowski (Author), Natalia Wawrusiewicz-Kurylonek (Author), Anja Eckstein (Author), Joanna Reszec (Author), Wlodzimierz Luczynski (Author), Kristian Johnson (Author), Adam Kretowski (Author), Alina Bakunowicz-Lazarczyk (Author), Maria Gorska (Author), Jacek Szamatowicz (Author), Lech Chyczewski (Author), Janusz Mysliwiec (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose. To evaluate the relationship between the expression of orbital tissue mRNA for FOXP3, CTLA-4/CD28/CD80/CD86, and CD40/CD40 and the severity of Graves' orbitopathy (GO). Material and Methods. Orbital tissue was obtained from 26 patients with GO, with mild (n=6) or severe GO (n=20), and...