SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells

• Main Authors: Joshua Jackson (Author), Lena Wischhof (Author), Enzo Scifo (Author), Anna Pellizzer (Author), Yiru Wang (Author), Antonia Piazzesi (Author), Debora Gentile (Author), Sana Siddig (Author), Miriam Stork (Author), Chris E. Hopkins (Author), Kristian Händler (Author), Joachim Weis (Author), Andreas Roos (Author), Joachim L. Schultze (Author), Pierluigi Nicotera (Author), Dan Ehninger (Author), Daniele Bano (Author)
• Format: Book
• Published: Elsevier, 2022-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Mitochondrial "retrograde" signaling may stimulate organelle biogenesis as a compensatory adaptation to aberrant activity of the oxidative phosphorylation (OXPHOS) system. To maintain energy-consuming processes in OXPHOS deficient cells, alternative metabolic pathways are functi...