Antinociceptive potency of a fluorinated cyclopeptide Dmt-c[D-Lys-Phe-p-CF3-Phe-Asp]NH2

• Main Authors: Justyna Piekielna-Ciesielska (Author), Adriano Mollica (Author), Stefano Pieretti (Author), Jakub Fichna (Author), Agata Szymaszkiewicz (Author), Marta Zielińska (Author), Radzisław Kordek (Author), Anna Janecka (Author)
• Format: Book
• Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Opioid peptides and opiate drugs such as morphine, mediate their analgesic effects, but also undesired side effects, mostly through activation of the mu opioid receptor. However, delta- and kappa-opioid receptors can also contribute to the analgesic effects of opioids. Recent findings showed that si...