Melittin kills A549 cells by targeting mitochondria and blocking mitophagy flux

• Main Authors: Xuan Li (Author), Zheng Li (Author), Yu-Qi Meng (Author), Hui Qiao (Author), Ke-Rong Zhai (Author), Zhen-Qing Li (Author), Shi-Lin Wei (Author), Bin Li (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTMelittin, a naturally occurring polypeptide found in bee venom, has been recognized for its potential anti-tumor effects, particularly in the context of lung cancer. Our previous study focused on its impact on human lung adenocarcinoma cells A549, revealing that melittin induces intracellula...