Actively priming autophagic cell death with novel transferrin receptor-targeted nanomedicine for synergistic chemotherapy against breast cancer

• Main Authors: Dong Mei (Author), Binlong Chen (Author), Bing He (Author), Haibin Liu (Author), Zhiqiang Lin (Author), Jialiang Lin (Author), Xiaoyan Zhang (Author), Ning Sun (Author), Libo Zhao (Author), Xiaoling Wang (Author), Qiang Zhang (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recently, considerable attention in the field of cancer therapy has been focused on the mammalian rapamycin target (mTOR), inhibition of which could result in autophagic cell death (ACD). Though novel combination chemotherapy of autophagy inducers with chemotherapeutic agents is extensively investig...