Fabrication of Intragastric Floating, Controlled Release 3D Printed Theophylline Tablets Using Hot-Melt Extrusion and Fused Deposition Modeling

• Main Authors: Bhupendra Raj Giri (Author), Eon Soo Song (Author), Jaewook Kwon (Author), Ju-Hyun Lee (Author), Jun-Bom Park (Author), Dong Wuk Kim (Author)
• 格式: 图书
• 出版: MDPI AG, 2020-01-01T00:00:00Z.
• 主题: article
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This work presents a novel approach for producing gastro-retentive floating tablets (GRFT) by coupling hot-melt extrusion (HME) and fused deposition three-dimensional printing (3DP). Filaments containing theophylline (THEO) within a hydroxypropyl cellulose (HPC) matrix were prepared using HME. 3DP t...