Stereological Estimation and Zonal Distribution of the Hepatotoxic Effects of Doxorubicin on the Female Albino Rat (Rattus Norvegicus)

• Main Authors: Khulud Nurani (Author), Anne Pulei (Author), Beda Olabu (Author), Jeremiah Munguti (Author), Talha Chaudhry (Author), Vincent Kipkorir (Author)
• Format: Book
• Published: University Library System, University of Pittsburgh, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Doxorubicin is an anti-neoplastic agent widely indicated for a variety of cancers. One of its adverse effects is hepatotoxicity which presents with hepatocyte necrosis, sinusoidal dilation, and fibrosis. However, there remains a dearth in the quantification and zonal distribution of this...