Whole-exome sequencing reveals ANO8 as a genetic risk factor for intrahepatic cholestasis of pregnancy

• Main Authors: Xianxian Liu (Author), Hua Lai (Author), Xiaoming Zeng (Author), Siming Xin (Author), Liju Nie (Author), Zhenyi Liang (Author), Meiling Wu (Author), Yu Chen (Author), Jiusheng Zheng (Author), Yang Zou (Author)
• Format: Book
• Published: BMC, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Intrahepatic cholestasis of pregnancy (ICP) is characterized by pruritus and cholestasis in late pregnancy and results in adverse pregnancy outcomes, including preterm delivery and birth weight, which are affected by the genetic and environmental background. However, until now, t...