Injectable Biodegradable Silica Depot: Two Months of Sustained Release of the Blood Glucose Lowering Peptide, Pramlintide

• Main Authors: Puneet Tyagi (Author), Mika Koskinen (Author), Jari Mikkola (Author), Sanjay Sarkhel (Author), Lasse Leino (Author), Asha Seth (Author), Shimona Madalli (Author), Sarah Will (Author), Victor G. Howard (Author), Helen Brant (Author), Dominic Corkill (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Diabetes mellitus is a major healthcare challenge. Pramlintide, a peptide analogue of the hormone amylin, is currently used as an adjunct with insulin for patients who fail to achieve glycemic control with only insulin therapy. However, hypoglycemia is the dominant risk factor associated with such a...