Therapeutic Development by Targeting the cGAS-STING Pathway in Autoimmune Disease and Cancer

• मुख्य लेखकों: Qiumei Li (लेखक), Shuoran Tian (लेखक), Jiadi Liang (लेखक), Jiqiang Fan (लेखक), Junzhong Lai (लेखक), Qi Chen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

DNA immune recognition regulation mediated by the cGAS-STING pathway plays an important role in immune functions. Under normal physiological conditions, cGAS can recognize and bind to invading pathogen DNA and activate the innate immune response. On the other hand, abnormal activation of cGAS or STI...