DNA and protein-generated chimeric molecules for delivery of influenza viral epitopes in mouse and humanized NSG transfer models

• Päätekijät: Nikolina M. Mihaylova (Tekijä), Iliyan K. Manoylov (Tekijä), Maria H. Nikolova (Tekijä), Jozsef Prechl (Tekijä), Andrey I. Tchorbanov (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

ABSTRACTPurified subunit viral antigens are weakly immunogenic and stimulate only the antibody but not the T cell-mediated immune response. An alternative approach to inducing protective immunity with small viral peptides may be the targeting of viral epitopes to immunocompetent cells by DNA and pro...