Infections in patients with rheumatoid arthritis receiving anti-cytokine therapy: biological mechanisms and clinical aspects

• Main Authors: C. Botsios (Author), P. Ostuni (Author), P. Sfriso (Author), A. Furlan (Author), U. Fiocco (Author), D. Sgarabotto (Author), S. Todesco (Author)
• Format: Book
• Published: PAGEPress Publications, 2003-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Different animal studies show that several proinflammatory cytokines are essential for natural resistance to specific infections, particularly versus intracellular organisms. However, uncontrolled overproduction of some proinflammatory cytokines, in diseases such as rheumatoid arthritis, can be just...