Evaluation of Dexamethasone-Induced Osteoporosis In Vivo Using Zebrafish Scales

• Main Authors: Siripat Chaichit (Author), Takuto Sato (Author), Huiqing Yu (Author), Yu-ki Tanaka (Author), Yasumitsu Ogra (Author), Takamasa Mizoguchi (Author), Motoyuki Itoh (Author)
• Format: Book
• Published: MDPI AG, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glucocorticoid-induced osteoporosis (GIOP) is a major cause of secondary osteoporosis, and the pathogenic mechanisms of GIOP remain to be elucidated. Here, we show a rapid dexamethasone-induced osteoporosis animal model using zebrafish scales. Intraperitoneal injection of dexamethasone over a 5-day...