A single trophectoderm biopsy at blastocyst stage is mathematically unable to determine embryo ploidy accurately enough for clinical use

• Principais autores: Norbert Gleicher (Autor), Jacob Metzger (Autor), Gist Croft (Autor), Vitaly A. Kushnir (Autor), David F. Albertini (Autor), David H Barad (Autor)
• Formato: Livro
• Publicado em: BMC, 2017-04-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Abstract Background It has become increasingly apparent that the trophectoderm (TE) at blastocyst stage is much more mosaic than has been appreciated. Whether preimplantation genetic screening (PGS), utilizing a single TE biopsy (TEB), can reliably determine embryo ploidy has, therefore, increasingl...