From concept to delivery: a yeast-expressed recombinant protein-based COVID-19 vaccine technology suitable for global access

• Main Authors: Peter J. Hotez (Author), Rakesh Adhikari (Author), Wen-Hsiang Chen (Author), Yi-Lin Chen (Author), Portia Gillespie (Author), Nelufa Y. Islam (Author), Brian Keegan (Author), Rakhi Tyagi Kundu (Author), Jungsoon Lee (Author), Zhuyun Liu (Author), Jason T. Kimata (Author), Numan Oezguen (Author), Jeroen Pollet (Author), Cristina Poveda (Author), Kay Razavi (Author), Shannon E. Ronca (Author), Ulrich Strych (Author), Syamala R. Thimmiraju (Author), Leroy Versteeg (Author), Maria Jose Villar-Mondragon (Author), Junfei Wei (Author), Bin Zhan (Author), Maria Elena Bottazzi (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction The development of a yeast-expressed recombinant protein-based vaccine technology co-developed with LMIC vaccine producers and suitable as a COVID-19 vaccine for global access is described. The proof-of-concept for developing a SARS-CoV-2 spike protein receptor-binding domain (RBD) anti...