Mitofusin2, as a Protective Target in the Liver, Controls the Balance of Apoptosis and Autophagy in Acute-on-Chronic Liver Failure

• मुख्य लेखकों: Ran Xue (लेखक), Jing Yang (लेखक), Lin Jia (लेखक), Xuemin Zhu (लेखक), Jing Wu (लेखक), Yueke Zhu (लेखक), Qinghua Meng (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Aim: Acute-on-chronic liver failure (ACLF) is closely related to mitochondrial dysfunction. Previous studies showed the vital role of mitofusin2 (Mfn2) in the regulation of mitochondrial function. However, the effect of Mfn2 on ACLF remains unknown. As one of mitochondrial-related pathways, BNIP3-me...