Design and analysis considerations for early phase clinical trials in hepatitis B (HBV) cure research: the ACTG A5394 study in persons with both HIV and HBV

With growing interest and efforts to achieve a hepatitis B (HBV) cure, HBV therapeutics have increasingly entered the clinical testing phase. In designing an early phase clinical trial aimed at HBV cure, the heterogeneity in participants and the choice of a biomarker endpoint that signals a cure req...

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Main Authors: Minhee Kang (Author), Jennifer C. Price (Author), Marion G. Peters (Author), Sharon R. Lewin (Author), Mark Sulkowski (Author)
Format: Book
Published: Elsevier, 2023-09-01T00:00:00Z.
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3rd Floor Main Library

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