The flavonoid fisetin ameliorates renal fibrosis by inhibiting SMAD3 phosphorylation, oxidative damage, and inflammation in ureteral obstructed kidney in mice

Background Renal fibrosis is characterized by the accumulation of extracellular matrix and inflammatory cells and kidney dysfunction, which is a major pathway in the progression of chronic kidney disease (CKD). Accumulating evidence indicates that oxidative stress plays a critical role in the initia...

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Main Authors: Ha Young Ju (Author), Jongwan Kim (Author), Sang Jun Han (Author)
Format: Book
Published: The Korean Society of Nephrology, 2023-05-01T00:00:00Z.
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