A Nitrobenzoyl Sesquiterpenoid Insulicolide A Prevents Osteoclast Formation via Suppressing c-Fos-NFATc1 Signaling Pathway

• Egile Nagusiak: Yanhui Tan (Egilea), Minhong Ke (Egilea), Zhichao Li (Egilea), Yan Chen (Egilea), Jiehuang Zheng (Egilea), Yiyuan Wang (Egilea), Xuefeng Zhou (Egilea), Gang Huang (Egilea), Xiaojuan Li (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2022-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

It is a viable strategy to inhibit osteoclast differentiation for the treatment of osteolytic diseases such as osteoporosis, rheumatoid arthritis and tumor bone metastases. Here we assessed the effects of insulicolide A, a natural nitrobenzoyl sesquiterpenoid derived from marine fungus, on receptor...