Nephropathy is aggravated by fatty acids in diabetic kidney disease through tubular epithelial cell necroptosis and is alleviated by an RIPK-1 inhibitor

• Main Authors: Qi Yu (Author), Ying Chen (Author), Youlu Zhao (Author), Shuo Huang (Author), Xiaohong Xin (Author), Lei Jiang (Author), Hui Wang (Author), Wenyan Wu (Author), Lei Qu (Author), Chengang Xiang (Author), Suxia Wang (Author), Gang Liu (Author), Li Yang (Author)
• Format: Book
• Published: Karger Publishers, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Diabetic kidney disease (DKD), one of the leading causes of end-stage renal disease, has complex pathogenic mechanisms and few effective clinical therapies. DKD progression is accompanied by the loss of renal resident cells, followed by chronic inflammation and extracellular matrix dep...