Spatiotemporally resolved metabolomics and isotope tracing reveal CNS drug targets

• Main Authors: Bo Jin (Author), Xuechao Pang (Author), Qingce Zang (Author), Man Ga (Author), Jing Xu (Author), Zhigang Luo (Author), Ruiping Zhang (Author), Jiangong Shi (Author), Jiuming He (Author), Zeper Abliz (Author)
• Format: Book
• Published: Elsevier, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Deconvolution of potential drug targets of the central nervous system (CNS) is particularly challenging because of the complicated structure and function of the brain. Here, a spatiotemporally resolved metabolomics and isotope tracing strategy was proposed and demonstrated to be powerful for deconvo...