Velvet antler polypeptide partially rescue facet joint osteoarthritis-like phenotype in adult β-catenin conditional activation mice

• Hlavní autoři: Wan-qing Xie (Autor), Yong-jian Zhao (Autor), Feng Li (Autor), Bing Shu (Autor), Shu-ru Lin (Autor), Li Sun (Autor), Yong-jun Wang (Autor), Hong-xin Zheng (Autor)
• Médium: Kniha
• Vydáno: BMC, 2019-07-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Abstract Background Wnt/β-catenin signaling pathway is closely related to osteoarthritis. In our preliminary study, β-catenin conditional activation (cAct) mice that specifically over-express β-catenin gene in cartilage chondrocyte exhibits osteoarthritis-like phenotype in the lumbar disc and knee j...