Immunoreactive Trypsinogen in Infants Born to Women with Cystic Fibrosis Taking Elexacaftor-Tezacaftor-Ivacaftor

• Main Authors: Payal Patel (Author), Jana Yeley (Author), Cynthia Brown (Author), Melissa Wesson (Author), Barbara G. Lesko (Author), James E. Slaven (Author), James F. Chmiel (Author), Raksha Jain (Author), Don B. Sanders (Author)
• Format: Book
• Published: MDPI AG, 2023-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Most people with cystic fibrosis (CF) are diagnosed following abnormal newborn screening (NBS), which begins with measurement of immunoreactive trypsinogen (IRT) values. A case report found low concentrations of IRT in an infant with CF exposed to the CF transmembrane conductance regulator (CFTR) mo...