Bispecific antibodies in cancer therapy: Target selection and regulatory requirements

• Main Authors: Yanze Sun (Author), Xinmiao Yu (Author), Xiao Wang (Author), Kai Yuan (Author), Gefei Wang (Author), Lingrong Hu (Author), Guoyu Zhang (Author), Wenli Pei (Author), Liping Wang (Author), Chengliang Sun (Author), Peng Yang (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In recent years, the development of bispecific antibodies (bsAbs) has been rapid, with many new structures and target combinations being created. The boom in bsAbs has led to the successive issuance of industry guidance for their development in the US and China. However, there is a high degree of si...