Forced degradation studies of ivabradine and in silico toxicology predictions for its new designated impurities

• Main Authors: Piotr ePikul (Author), Marzena eJamrógiewicz (Author), Joanna eNowakowska (Author), Weronika eHewelt-Belka (Author), Krzesimir eCiura (Author)
• Format: Book
• Published: Frontiers Media S.A., 2016-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

All activities aim to eliminate genotoxic impurities or/and protect the medicinal compounds against degradation. There is a need to monitor impurities from all classification groups, so that ivabradine forced degradation studies were performed. Ivabradine proved to be a quite durable active substanc...