Forced degradation studies of ivabradine and in silico toxicology predictions for its new designated impurities

• Үндсэн зохиолчид: Piotr ePikul (Зохиогч), Marzena eJamrógiewicz (Зохиогч), Joanna eNowakowska (Зохиогч), Weronika eHewelt-Belka (Зохиогч), Krzesimir eCiura (Зохиогч)
• Формат: Ном
• Хэвлэсэн: Frontiers Media S.A., 2016-05-01T00:00:00Z.
• Нөхцлүүд: article
• Онлайн хандалт: Connect to this object online.

All activities aim to eliminate genotoxic impurities or/and protect the medicinal compounds against degradation. There is a need to monitor impurities from all classification groups, so that ivabradine forced degradation studies were performed. Ivabradine proved to be a quite durable active substanc...