Preparation of curcumin self-micelle solid dispersion with enhanced bioavailability and cytotoxic activity by mechanochemistry

Preparation of curcumin self-micelle solid dispersion with enhanced bioavailability and cytotoxic activity by mechanochemistry

An amorphous solid dispersion (SD) of curcumin (Cur) with disodium glycyrrhizin (Na2GA) was prepared by mechanical ball milling. Curcumin loaded micelles were self-formed by Na2GA when SD dissolved in water. The physical properties of Cur SD in solid state were characterized by differential scanning...

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Main Authors: Qihong Zhang (Author), Nikolay E. Polyakov (Author), Yulia S. Chistyachenko (Author), Mikhail V. Khvostov (Author), Tatjana S. Frolova (Author), Tatjana G. Tolstikova (Author), Alexandr V. Dushkin (Author), Weike Su (Author)
Format: Book
Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
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