The Anticancer Effects of Atractylenolide III Associate With the Downregulation of Jak3/Stat3-Dependent IDO Expression

• Egile Nagusiak: Jun-bao Liu (Egilea), Dan Chen (Egilea), Ting-ting Bao (Egilea), Fang-tian Fan (Egilea), Chen Yu (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2020-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Indoleamin-2,3-dioxygenase-1 (IDO) has been identified as a checkpoint protein involved in generating the immunosuppressive tumor microenvironment that supports tumor growth. It has been reported that atractylenolide III (ATLIII) has anticancer and immune modulatory effects. This study is...