Evaluation of the in vivo genotoxicity of liposomal formulation for delivering anticancer estrogenic derivative (ESC8) in a mouse model

• Main Authors: Ajaz Ahmad (Author), Basit Latief Jan (Author), Mohammad Raish (Author), Hari Krishna Reddy Rachamalla (Author), Rajkumar Banerjee (Author), Debabrata Mukhopadhyay (Author), Khalid M. Alkharfy (Author)
• Format: Book
• Published: Elsevier, 2019-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The genotoxic potential of glucocorticoid receptor (GR)-targeted liposomal formulations of the anticancer drug molecule ESC8 was studied in vivo. A methodical literature review discovered no previous studies on the genotoxicity of ESC8. Genotoxicity was assessed in both male and female mice by vario...