The role of RICTOR amplification in targeted therapy and drug resistance

• Main Authors: Deze Zhao (Author), Man Jiang (Author), Xiaochun Zhang (Author), Helei Hou (Author)
• פורמט: ספר
• יצא לאור: BMC, 2020-02-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Abstract The emergence of tyrosine kinase inhibitors (TKIs) has changed the current treatment paradigm and achieved good results in recent decades. However, an increasing number of studies have indicated that the complex network of receptor tyrosine kinase (RTK) co-activation could influence the cha...