Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni.

• Main Authors: Holly M Craven (Author), Riccardo Bonsignore (Author), Vasilis Lenis (Author), Nicolo Santi (Author), Daniel Berrar (Author), Martin Swain (Author), Helen Whiteland (Author), Angela Casini (Author), Karl F Hoffmann (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Schistosomiasis is a neglected tropical disease that currently affects over 250 million individuals worldwide. In the absence of an immunoprophylactic vaccine and the recognition that mono-chemotherapeutic control of schistosomiasis by praziquantel has limitations, new strategies for managing diseas...